Engineering Cell Interfaces
Delivery of large molecular cargoes, such as mRNA, DNA, and proteins has become critical for biological research and clinical therapies. However, the basic act of transporting exogenous material into and out of a cell is still a major obstacle, and a fascinating materials science challenge. Here, we create nanostructures designed to act as "pipelines" into and out of the cell. These conduits provide some of the highest efficiencies, widest range of cell types, and variety of cargoes available. Facile cellular access is changing how we think about cell manipulation and therapy development. New research is exploring cellular sampling and control systems, as well as single cell electrical interfaces.
Cells are non-destructively accessed by Nanostraw arrays